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The Prevention Research Center of the Pacific Institute for Research and Evaluation was formed in 1983 as a national center for prevention research. PRC's focus is on conducting research to better understand the social and physical environments that influence individual behavior that leads to alcohol and drug misuse.

PRC is one of fifteen centers sponsored by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), of the U.S. National Institutes of Health, and is the only one that specializes in prevention. The Center's research program integrates such disciplines as anthropology, economics, epidemiology, public health, law and policy science, psychology and sociology. The goal of this basic scientific research is to understand the individual, social, political and environmental circumstances related to adverse health outcomes.

The Center has a mission to:

Undertake innovative prevention research and approaches that contribute to informed decisions about cost-effective prevention programs and policies at the local, state and national levels.

Summarize new and existing knowledge about prevention theories, policies, and programs, and disseminate this information to professional, academic, and community audiences.

Provide multidisciplinary training and research opportunities.